Cryo Equipment

CRYO-S®

Painless

Cryoanalgesia

and its mechanisms

Clinical application

CRYO-S® Painless

Characteristics

CRYO-S® Painless

High quality

CRYO-S® Painless

Video of pain relief

procedure

PHARMASCO COMPANY - the exclusive

distributor of CRYO-S® Painless in UKRAINE

CRYO-S® Painless is a high-tech device

for cryoneurolysis. An innovative method of chronic pain treatment

Cryoanalgesia

is a therapeutic method based on the temporary interruption of sensory functions in selected structures of the nervous system by application of low temperature. Cryoanalgesia is becoming increasingly popular as an innovative method for relieving pain. This method uses the process of analgesia, during which the ice crystals created by the cryosurgical system destroy the elements of the nerve tissue carring pain information. Cryoanalgesia does not damage nerve structures permanently that is why nerve tissue can regenerate slowly without the risk of post-procedure neuroma. Cryoanalgesia is a minimally invasive and safe procedure recommended mainly in cases where traditional methods have been proved as ineffective.

Mechanism of cryoanalgesia

Large myelin sensory or mixed nerves are responsible for conduction of pain impulses from the periphery to the center. Cryoanalgesia is indicated for patients with chronic pain, the intensity of which exceeds the level of "5" on the visual analog scale (VAS).

During interventional cryoanalgesia, an ice ball destroys the axon of the neuron distally and slightly closer to the site of injury with the appearance of Valerian cell degeneration there. The axon and its myelin sheath are damaged, but Schwann cells, endoneurium, perineurium, and epineurium remain intact. Thus, the pain disappears

The rate of outgrowth nerve fibre is about 1 mm per day, so that the final recovery of nerve conduction depends on the quality of freezing. Even if the peripheral nerve structures recover after some weeks, the functionality of the sensory nerve still remains blocked. In mixed nerves, mobility functions recover much faster than in sensory. Cryoanalgesia is also a recommended and safe method for the treatment of pain resulting from mixed nerve damage (eg, «scapular periarthritis»).

Complete sensory nerve recovery, including its functionatily, takes place within 6-12 months after the Cryoanalgesia procedure. During this period, the patient does not feel pain or pain is significantly reduced.

Clinical application CRYO-S ® Painless

• Secondary craniofacial pain, trigeminal neuralgia, posterior auricular neuralgia, and glossopharyngeal neuralgia

• Chest wall pain with multiple conditions, including post-thoracotomy neuromas, persistent pain after rib fractures and post herpetic neuralgia in the chest

• Abdominal and pervic pain secondary to ilioinguinal, iliohypogastic, genitofemoral, subgastric or pudendal neuralgia

• Low back pain and lower extremity pain secondary to lumbar facet joints pathology, pseudosciatica

• Pain involving intraspinous ligament of supragluteal nerve

• Sacroiliac joint pain, cluneal neuralgia, obturator neuritis. Primary or secondary pain in relation to: infrapatellar branch of the subcutaneous nerve, anterior cutaneous nerve of the thigh, knee nerve after total knee arthroplasty

• Different types of peripheral neuropathy

• Trigger zones

• Phantom pain

• Upper extremity pain secondary to suprascapular neuritis and other conditions of peripheral neuritis

• Diabetic neuropathy

• Morton's neuroma, heel pain

Characteristics CRYO-S ® Painless

Power requirements: Power 100 ÷ 240 V (50/60 Hz) AC

Maximum power consumption 150 VA

Cooling medium CO2- 78 ° C or N2O- 89 ° C

Maximum pressure 70 bar (CO2) and 55 bar (N2O)

Working pressure 48 ÷ 65 bar (CO2), 38-53 bar (N2O)

Liquid crystal touch screen

Voice information system (information on key indicators during the procedure)

Convenient control with a two-button pedal

Automatic / manual control of flow parameters

Automatic gas pressure control

Freezing temperature control

Two operating modes (automatic and manual)

Built-in neurostimulator with 2 types of stimulation (sensory and motor) and various options of manual settings

for motor stimulation: 1 and 2 Hz

for sensory stimulation: 50, 100, 150, 200 Hz

Pulse width settings: 0.1, 0.2, 0.5, 1.0, 2.0-5.0 ms

Advantages of cryoanalgesia

• No neuroma formation - no risk of secondary pain

• High efficiency: pain reduction from 6 months to 2 years

• No scar tissue formation

• Suitable for patients with pacemakes and other stimulants

• No risk of vessel proliferation and obliteration

• Can be repeated - nerve grows back

• Simple diagnosis: fluoroscopy or ecograghy

• Percutaneous procedure, microinvasive under local anesthesia

• Fast return to normal activities - no hospitalization

• Can be performed under USG or X-ray

Quality that meets the high requirements of international and European legislation

Production of CRYO-S® Painless meets the requirements of ISO 13485: 2012CRYO-S® Painless is CE marked 2274.
The safety and high quality of CRYO-S® Painless is confirmed by certificates of conformity in accordance with the requirements of the MDD Directive 93/42 / EEC on medical devices.
The local Ukrainian regulatory institution has confirmed compliance with all the above European quality standards